Prescription Medication Information


Meridia (Sibutramine Hcl) is used to reduce excess body weight (obesity) in addition to a reduced calorie diet and exercise.

How to take Meridia

Meridia should be taken exactly as directed by your doctor, usually once daily. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because Meridia can be habit-forming.

Also, if used for a longer period of time, do not suddenly stop using this drug without your doctor's approval. Over time, Meridia may not work as well as it did at the beginning. You should consult your doctor if weight increases.

Side Effects

Dry mouth, drowsiness, constipation and difficulty sleeping may occur when taking Meridia. If these effects persist or worsen, notify your doctor promptly.

Drug Interactions
Before using Meridia, you should inform your physician of all nonprescription and prescription medication you may use, especially other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs which can cause drowsiness, including certain antihistamines (e.g., diphenhydramine), sedatives and anti-seizure drugs. Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. Consult your pharmacist. MAO Inhibitors (see above) and this drug should not be taken together. If an MAO Inhibitor or this drug is stopped, wait 2 weeks before starting the other drug.

Before using Meridia, tell your doctor your entire medical history, including any allergies (especially drug allergies), liver or kidney disease, high blood pressure or heart disease, history of stroke or seizures, certain eating disorders (e.g., anorexia nervosa), glaucoma (narrow angle), or history of gallstones. Limit alcohol intake, as it may worsen certain side effects of Meridia.

It is recommended that women of child-bearing age should use effective birth control while taking this medication. Meridia is not recommended for use during pregnancy. Consult your doctor before using this drug. It is not known whether Meridia is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Elderly patients may be more sensitive to the effects of Meridia. Use cautiously.

Missed Dose
If you miss a dose of Meridia, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Meridia should be used in addition to a reduced calorie diet. Do not share this medication with others. Blood pressure and pulse may be measured and laboratory tests performed to monitor side effects. Keep Meridia and all medications out of the reach of children.

This information regarding Meridia is intended to supplement, not substitute the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of Meridia is safe, appropriate, or effective for you. Consult your healthcare professional before using Meridia.

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